Cortisol and the sex hormones are all made from the same precursor hormone, pregnenolone.
Similar effects on behavior and pregnenolone sulfate levels by DHEA are reported for androgenized females Robel et al,
The cartilage has been worn away either through use or as the result of an autoimmune disorderso the joints swell up to prevent the bones from rubbing against each other.
That's a severe drop in the precursor hormone, which leads to a drop in ALL the hormones resulting from pregnenolone.
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Moreover, therapies that address other conditions such as mood disorders may positively impact sexual desire.
Low dehydroepiandrosterone and ischemic heart disease in middle-aged men: